Fermentation supernatant from King Oyster mushroom may protect against leaky gut

The in vitro study, published in Nutrients, highlighted the potential of the fermentation supernatant of King Oyster mushroom (Pleurotus eryngii), also known as King Trumpet mushroom, for managing gut barrier dysfunction or “leaky gut.”

“We have elucidated a dual protective capacity of FS-PEWS [Pleurotus eryngii mushroom fermentation supernatant], specifically its remarkable ability to preserve tight junction integrity while concurrently modulating both paracellular and transcellular permeability under the stress of secondary bile acid exposure,” wrote researchers from the Nutrition-Gut-Brain Interactions Research Centre at Örebro…