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(Health-NewsWire.Net, September 23, 2015 ) Osteoarthritis (OA) constitutes a growing public health burden, and is the most common cause of musculoskeletal disability across the globe. Intra-articular viscosupplementation with hyaluronic acid (HA) has become an increasingly accepted therapeutic alternative to knee replacement surgery in the symptomatic management of OA over the past decade. Going forward, palliative pain treatments are likely to continue to fare well as healthcare reform kicks in and lag times for knee replacement become the norm. Growth of the viscosupplementation market will be highest in the US and the Asia-Pacific (APAC) region, where there is a significant pent-up demand for early intervention in the management of OA.
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The increasing prevalence of OA and the lower cost of prescribing viscosupplementation compared with knee replacement surgery have prompted the medical community to take a closer look at this therapy. However, there is a growing concern among physicians that the updated American Academy of Orthopaedic Surgeons (AAOS) and Osteoarthritis Research Society International (OARSI) treatment guidelines for knee OA will result in increased insurance denials for viscosupplementation. Moving forward, industry consolidation and intense competition in the viscosupplementation arena will cause increasing numbers of companies to augment their research efforts to differentiate their products from the lower-end competitors. The motivation to incorporate the favorable properties of different agents into a more effective viscosupplementation product has led to the manipulation and development of next-generation HA formulations consisting of not only HAs, but also pharmaceuticals, such as corticosteroids.
Highlights
Key Questions Answered
- Future growth in the viscosupplementation market lies in the one-injection segment. What are the current adoption trends in different geographies? How will one-injection segment drive the market revenue growth in the upcoming years?
- In the US, some commercial insurers have completely excluded viscosupplementation treatment from their coverage. Even when the criteria for coverage have clearly been met by the patient, denials are common. Has this impacted the procedure volume growth in the US viscosupplementation market?
- Reimbursement is the single greatest barrier to the market growth for viscosupplementation procedures. How does the current payer mix look like in different countries?
- In recent years, there has been an expansion in the use of intra-articular HA viscosupplementation for treating OA at hips, shoulders, and other small joints. What are the current adoption trends in different regions?
- Because the most prevalent treatment regimen varies from region to region, the competitive landscape in the viscosupplementation space can be quite different across the geographies covered in this report. Who are the leading players in the viscosupplementation market in different countries?
Reasons to buy
- What Do Physicians Think quotes provide a unique insight into how healthcare professionals are reacting to events within the industry, and what their responses could mean for industry strategists. This information is essential for all strategic decision makers in every organization allowing them to act on high quality information.
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Table of Contents
1.1 List of Tables 13
1.2 List of Figures 17
2 Introduction 20
2.1 Catalyst 20
2.2 Related Reports 20
3 Treatment Modalities Overview 22
3.1 Treatment Paradigm 22
3.1.1 Physical Therapies 22
3.1.2 Medications 22
3.1.3 Hyaluronic Acid Viscosupplementation 23
3.1.4 Surgical Intervention 25
4 Industry Overview 26
4.1 Procedural Trends 26
4.1.1 Overview 26
4.1.2 US 30
4.1.3 5EU 33
4.1.4 Asia-Pacific 37
4.1.5 South America 42
4.2 Market Access 45
4.2.1 US 45
4.2.2 5EU 46
4.2.3 Asia-Pacific 47
4.2.4 South America 47
4.3 Reimbursement 48
4.3.1 US 48
4.3.2 5EU 52
4.3.3 Asia-Pacific 58
4.3.4 South America 61
4.4 Mergers and Acquisitions/Key Partnerships 62
4.4.1 Meda AB Acquires Rottapharm|Medaus for $3.1 Billion (October 2014) 62
4.4.2 Founders of Anteis Establish Aptissen (March 2014) 63
4.4.3 Bioventus Acquires Durolane Assets from Galderma (February 2014) 63
4.4.4 Zimmer to Combine with Biomet in a Transaction Valued at $13.35 Billion (April 2014) 63
4.4.5 Johnson & Johnson Acquires Synthes for $19.7 Billion (June 2012) 64
5 Market Drivers, Opportunities, and Barriers 65
5.1 Driver: Rising Prevalence of OA 65
5.2 Driver: Multimodal Treatment Paradigm for OA 66
5.3 Driver: Viscosupplementation Delays Total Knee Replacement 67
5.4 Driver: Side Effects of NSAIDs, Corticosteroids, and Narcotics 68
5.5 Driver: Direct-To-Consumer Marketing 70
5.6 Opportunity: Expanding Indications 71
5.7 Opportunity: New-Generation HA Derivatives 72
5.8 Opportunity: Increased Use After Arthroscopic Surgeries 74
5.9 Opportunity: Self-Pay Market 74
5.10 Opportunity: Emerging Countries 76
5.11 Barrier: Unfavorable Reimbursement Scenario 76
5.12 Barrier: Pricing Erosion 77
5.13 Barrier: Cost-Effective Pharmacological Therapies 78
5.14 Barrier: Will The Rising Popularity of PRP Injection Impact the Viscosupplementation Market? 78
5.15 Barrier: Cost-Conscious Patients in Emerging Countries 81
6 Unmet Needs 83
6.1 Lack of Consensus on Clinical Efficacy of Viscosupplementation in Knee OA 83
6.2 Insufficient Evidence to Prove the Clinical Efficacy of Viscosupplementation in Other Joints 85
6.3 Better Understanding of the Basic Science 87
6.4 Ultrasound-Guided Injection 90
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