(Health-NewsWire.Net, May 31, 2016 ) This Competitive Intelligence report about Biosimilar & Biosuperior Therapeutic Antibodies updates the competitive landscape of biosimilar therapeutic antibodies as of May 2016. The report evaluates the the first wave of biosimilar recombinant monoclonal antibodies in comparison with the corresponding originator antibodies and biosuperior antibodies against the same target. The report also describes the next wave of potential biosimilar versions of therapeutic antibodies loosing patent protection in the time frame of 2019 – 2023. The report specifically lists for each target the branded products with their 2015 sales and up-side indications in development, as well as biosuperior and biosimilar antibody drug candidates in development.
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The report includes a compilation of marketed, approved and currently active projects in research and development of biosimilar and biosuperior therapeutic antibodies against commercially and clinically validated targets relevant for the first wave of biosimilar antibodies (VEGF, TNF, Her2, CD20, EGF-R). Relevant first wave originator therapeutic antibodies are Humira, Enbrel, Remicade, Avastin, Lucentis, Eylea, Herceptin, Rituxan/MabThera and Erbitux. Second generation therapeutic antibodies against these targets such as Symponi, Cimzia, Cyramza, Perjeta, Arrzera are also subject of biosimilar activities.
The report also addresses the slowly emerging second wave of biosimilar antibody activities against originator therapeutic antibodies such as abatacept, alemtuzumab, denosumab, eculizumab, omalizumab, pavilizumab, tocilizumab, and ustekinumab.
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Table of Content
A) 2015 SALES OF THERAPEUTIC ANTIBODIES Overview: 2015 Biologics Sales per Class of Products Overview: 2015 Therapeutic Antibody Sales per Class of Products Blockbuster Therapeutic Antibodies in 2015 Anti-TNF Antibody Sales in 2015 Cancer Antibody Sales in 2015 Other Anti-Inflammatory Antibody Sales in 2015 Ophthalmic Antibody Sales in 2015 Cardiometabolic & Anti-Infective Antibody Sales in 2015 B) BIOSIMILAR AND BIOSUPERIOR ANTI-TNF ANTIBODIES – 2016 UPDATE 1. Originator Anti-TNF Antibodies Approved and Marketed Indications of anti-TNF Antibodies in Regulated Markets 2015 SALES OF ANTI-TNF ANTIBODIES Sales of Anti-TNF Antibodies in Q1/2016 Humira Pipeline of Recently Approved Indications & Upside Developments Remicade Pipeline of Recent Approvals & Upside Indications Enbrel Pipeline of Upside Indications Simponi Pipeline of Recent Approvals & Upside Indications Cimzia Pipeline of Recent Approvals & Upside Indications Defense Strategies against Biosimilar Anti-TNF Antibodies 2. Biosuperior Anti-TNF Antibodies Non-Antibody Anti-TNF Biosuperiors Anti-TNF Biosuperior Antibodies 3. Biosimimilar Anti-TNF Antibodies Humira Biosimilar Antibodies: Developments in Regulated Markets Developments in Less Regulated Markets Enbrel Biosimilar Antibodies: Developments in Regulated Markets Developments in Less Regulated Markets Remicade Biosimilar Antibodies: Developments in Regulated Markets Developments in Less Regulated Market Simponi & Cimzia Biosimilar Antibodies
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